The Effect of Cystoscopy on PSA Levels in Patients with Urologic Diseases


Bahar Bastani 1 , Ashkan Heshmatzade Behzadi 2 , * , Mohammad Amin Abbasi 3 , Jaleh Hassanloo 3 , Mahsa Sedaghati 3 , Yasamin Honarbakhsh 3 , Amir Poya Akasheh 3 , Mohsen Alghasi 3 , Parviz Rafiezadeh 3 , Maryam Masouminia 3 , Koosha Kamali 3

1 Nephrology Devision, Saint Louis University, USA

2 Urology Department Research Center, Iran University of Medical Sciences and Health Services,, IR-Iran

3 Nephrology and Urology Research Center, Baqiyatallah University of Medical Sciences, IR-Iran

How to Cite: Bastani B, Behzadi A, Abbasi M, Hassanloo J, Sedaghati M, et al. The Effect of Cystoscopy on PSA Levels in Patients with Urologic Diseases, Nephro-Urol Mon. Online ahead of Print ; 2(1):251-254.


Nephro-Urology Monthly: 2 (1); 251-254
Article Type: Research Article
Received: April 27, 2009
Accepted: May 30, 2009


Background and Aims: There is controversy on change of PSA levels after some urological procedures such as cystoscopy. In this study, we evaluated the effect of cystoscopy on PSA levels in patients with urologic diseases.

Methods: In a before-after study, 190 patients with urologic diseases such as relapsing UTI, urinary incontinency, hematuria, TCC follow up, DJ catheter removal and urinary retention were investigated. PSA levels were measured before and after cystoscopy.

Results: Mean age of patients was 6313 years. Mean duration of procedure was 2.51.2 minutes. Total PSA level increased in all groups after cystoscopy. More changes were found in patients with urinary retention (P<0.01). There was a relation between patients' ages and primary and secondary PSA levels (P=0.0001). Moreover there was a statistically significant direct relation between the PSA levels and the duration of procedures in different groups of patients (P=0.001).

Conclusion: Total PSA increases after cystoscopy and the level of PSA is higher in patients with urinary retention and change in level of PSA was higher in these patients. The results can have implications for the screening for prostate cancer patients.

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