Nephro-Urology Monthly

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Pulmonary and Chest Wall Metastasectomy in Urogenital Tumors: A Single Center Experience and Review of Literature

Seyd Hossein Fattahi Masoum 1 , Behzad Feizzdeh Kerigh 2 , * and Alireza Goreifi 3
Authors Information
1 Transplant Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
2 Minimally Invasive Surgery Research Center, Kidney Transplantation Complications Research Center, Ghaem Medical Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
3 Department of Urology, Mashhad University of Medical Sciences, Mashhad, IR Iran
Article information
  • Nephro-Urology Monthly: May 01, 2014, 6 (3); e17258
  • Published Online: May 3, 2014
  • Article Type: Research Article
  • Received: January 7, 2014
  • Accepted: March 15, 2014
  • DOI: 10.5812/numonthly.17258

To Cite: Fattahi Masoum S H, Feizzdeh Kerigh B, Goreifi A. Pulmonary and Chest Wall Metastasectomy in Urogenital Tumors: A Single Center Experience and Review of Literature, Nephro-Urol Mon. 2014 ; 6(3):e17258. doi: 10.5812/numonthly.17258.

Copyright © 2014, Nephrology and Urology Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Pfannschmidt J, Egerer G, Bischof M, Thomas M, Dienemann H. Surgical intervention for pulmonary metastases. Dtsch Arztebl Int. 2012; 109(40): 645-51[DOI][PubMed]
  • 2. Younes RN, Haddad F, Ferreira F, Gross JL. [Surgical removal of pulmonary metastasis: prospective study in 182 patients]. Rev Assoc Med Bras. 1998; 44(3): 218-25[PubMed]
  • 3. Kim JJ, Park JK, Wang YP. Surgical resection of pulmonary metastasis from renal cell carcinoma. Korean J Thorac Cardiovasc Surg. 2011; 44(2): 159-64[DOI][PubMed]
  • 4. Heidenreich A, Wilop S, Pinkawa M, Porres D, Pfister D. Surgical resection of urological tumor metastases following medical treatment. Dtsch Arztebl Int. 2012; 109(39): 631-7[DOI][PubMed]
  • 5. Beisland C, Medby PC, Beisland HO. Presumed radically treated renal cell carcinoma--recurrence of the disease and prognostic factors for subsequent survival. Scand J Urol Nephrol. 2004; 38(4): 299-305[PubMed]
  • 6. Mekhail TM, Abou-Jawde RM, Boumerhi G, Malhi S, Wood L, Elson P, et al. Validation and extension of the Memorial Sloan-Kettering prognostic factors model for survival in patients with previously untreated metastatic renal cell carcinoma. J Clin Oncol. 2005; 23(4): 832-41[DOI][PubMed]
  • 7. Staehler M. The role of metastasectomy in metastatic renal cell carcinoma. Nat Rev Urol. 2011; 8(4): 180-1[DOI][PubMed]
  • 8. Tsakiridis K, Visouli AN, Zarogoulidis P, Mpakas A, Machairiotis N, Stylianaki A, et al. Lost in time pulmonary metastases of renal cell carcinoma: complete surgical resection of metachronous metastases, 18 and 15 years after nephrectomy. J Thorac Dis. 2012; 4: 69-73[DOI][PubMed]
  • 9. Chen F, Fujinaga T, Shoji T, Miyahara R, Bando T, Okubo K, et al. Pulmonary resection for metastasis from renal cell carcinoma. Interact Cardiovasc Thorac Surg. 2008; 7(5): 825-8[DOI][PubMed]
  • 10. Pogrebniak HW, Haas G, Linehan WM, Rosenberg SA, Pass HI. Renal cell carcinoma: Resection of solitary and multiple metastases. The Annals of Thoracic Surgery. 1992; 54(1): 33-8[DOI]
  • 11. Pfannschmidt J, Klode J, Muley T, Dienemann H, Hoffmann H. Nodal involvement at the time of pulmonary metastasectomy: experiences in 245 patients. Ann Thorac Surg. 2006; 81(2): 448-54[DOI][PubMed]
  • 12. Pastorino U, Buyse M, Friedel G, Ginsberg RJ, Girard P, Goldstraw P, et al. Long-term results of lung metastasectomy: Prognostic analyses based on 5206 cases. J Thoracic Cardiovasc Surg 1997; 113(1): 37-49[DOI]
  • 13. Tanguay S, Swanson DA, Putnam JBJ. Renal Cell Carcinoma Metastatic to the Lung: Potential Benefit in the Combination of Biological Therapy and Surgery. J Urol. 1996; 156(5): 1586-9[DOI]
  • 14. Kanzaki R, Higashiyama M, Fujiwara A, Tokunaga T, Maeda J, Okami J, et al. Long-term results of surgical resection for pulmonary metastasis from renal cell carcinoma: a 25-year single-institution experience. Eur J Cardiothorac Surg. 2011; 39(2): 167-72[DOI][PubMed]
  • 15. Shiono S, Yoshida J, Nishimura M, Nitadori J, Ishii G, Nishiwaki Y, et al. Late pulmonary metastasis of renal cell carcinoma resected 25 years after nephrectomy. Jpn J Clin Oncol. 2004; 34(1): 46-9[PubMed]
  • 16. Kawamukai K, Di Saverio S, Antonacci F, Lacava N, Boaron M. Mediastinal germ cell tumour with massive pulmonary involvement. BMJ Case Rep. 2011; 2011[DOI][PubMed]
  • 17. Liu D, Abolhoda A, Burt ME, Martini N, Bains MS, Downey RJ, et al. Pulmonary metastasectomy for testicular germ cell tumors: A 28-year experience. The Annals of Thoracic Surgery. 1998; 66(5): 1709-14[DOI]
  • 18. Einhorn LH, Williams SD, Mandelbaum I, Donohue JP. Surgical resection in disseminated testicular cancer following chemotherapeutic cytoreduction. Cancer. 1981; 48(4): 904-8[DOI]
  • 19. Murphy BR, Breeden ES, Donohue JP, Messemer J, Walsh W, Roth BJ, et al. Surgical salvage of chemorefractory germ cell tumors. J Clin Oncol. 1993; 11(2): 324-9[PubMed]
  • 20. Wood DP, Herr HW, Motzer RJ, Reuter V, Sogani PC, Morse MJ, et al. Surgical resection of solitary metastases after chemotherapy in patients with nonseminomatous germ cell tumors and elevated serum tumor markers. Cancer. 1992; 70(9): 2354-7[DOI]
  • 21. Giannarini G, Kessler TM, Thoeny HC, Nguyen DP, Meissner C, Studer UE. Do patients benefit from routine follow-up to detect recurrences after radical cystectomy and ileal orthotopic bladder substitution? Eur Urol. 2010; 58(4): 486-94[DOI][PubMed]
  • 22. Volkmer BG, Kuefer R, Bartsch GC, Jr, Gust K, Hautmann RE. Oncological followup after radical cystectomy for bladder cancer-is there any benefit? J Urol. 2009; 181(4): 1587-93[DOI][PubMed]
  • 23. von der Maase H, Hansen SW, Roberts JT, Dogliotti L, Oliver T, Moore MJ, et al. Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study. J Clin Oncol. 2000; 18(17): 3068-77[PubMed]
  • 24. Cowles RS, Johnson DE, McMurtrey MJ. Long-term results following thoracotomy for metastatic bladder cancer. Urology. 1982; 20(4): 390-2[DOI]
  • 25. Siefker-Radtke AO, Walsh GL, Pisters LL, Shen Y, Swanson DA, Logothetis CJ, et al. Is there a role for surgery in the management of metastatic urothelial cancer? The M. D. Anderson experience. J Urol. 2004; 171(1): 145-8[DOI][PubMed]
  • 26. Abe T, Shinohara N, Harabayashi T, Sazawa A, Maruyama S, Suzuki S, et al. Impact of multimodal treatment on survival in patients with metastatic urothelial cancer. Eur Urol. 2007; 52(4): 1106-13[DOI][PubMed]
  • 27. Lehmann J, Suttmann H, Albers P, Volkmer B, Gschwend JE, Fechner G, et al. Surgery for metastatic urothelial carcinoma with curative intent: the German experience (AUO AB 30/05). Eur Urol. 2009; 55(6): 1293-9[DOI][PubMed]
  • 28. Siefker-Radtke AO, Dinney CP, Shen Y, Williams DL, Kamat AM, Grossman HB, et al. A phase 2 clinical trial of sequential neoadjuvant chemotherapy with ifosfamide, doxorubicin, and gemcitabine followed by cisplatin, gemcitabine, and ifosfamide in locally advanced urothelial cancer: final results. Cancer. 2013; 119(3): 540-7[DOI][PubMed]
  • 29. Svatek RS, Siefker-Radtke A, Dinney CP. Management of metastatic urothelial cancer: the role of surgery as an adjunct to chemotherapy. Can Urol Assoc J. 2009; 3(6 Suppl 4)-31[PubMed]
  • 30. Fabozzi SJ, Schellhammer PF, El-Mahdi AM. Pulmonary metastases from prostate cancer. Cancer. 1995; 75(11): 2706-9[DOI]
  • 31. Saitoh H, Hida M, Shimbo T, Nakamura K, Yamagata J, Satoh T. Metastatic patterns of prostatic cancer: Correlation between sites and number of organs involved. Cancer. 1984; 54(12): 3078-84[DOI]
  • 32. Goto T, Maeshima A, Oyamada Y, Kato R. Solitary pulmonary metastasis from prostate sarcomatoid cancer. World J Surg Oncol. 2010; 8: 101[DOI][PubMed]
  • 33. Picchio M, Briganti A, Fanti S, Heidenreich A, Krause BJ, Messa C, et al. The role of choline positron emission tomography/computed tomography in the management of patients with prostate-specific antigen progression after radical treatment of prostate cancer. Eur Urol. 2011; 59(1): 51-60[DOI][PubMed]
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