Nephro-Urology Monthly

Published by: Kowsar

Evaluation of Sarcopenia in Renal Transplant Recipients

Nihal Ozkayar 1 , * , Bulent Altun 2 , Meltem Halil 3 , Mehmet E. Kuyumcu 3 , Gunes Arik 2 , Yusuf Yesil 3 , Tolga Yildirim 2 , Rahmi Yilmaz 2 , Servet Ariogul 3 and Cetin Turgan 2
Authors Information
1 Department of Nephrology, Ankara Numune Education and Research Hospital, Ankara, Turkey
2 Department of Nephrology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
3 Division of Geriatric Medicine, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Article information
  • Nephro-Urology Monthly: July 01, 2014, 6 (4); e20055
  • Published Online: July 5, 2014
  • Article Type: Research Article
  • Received: May 7, 2014
  • Revised: June 23, 2014
  • Accepted: June 26, 2014
  • DOI: 10.5812/numonthly.20055

To Cite: Ozkayar N, Altun B, Halil M, E. Kuyumcu M, Arik G, et al. Evaluation of Sarcopenia in Renal Transplant Recipients, Nephro-Urol Mon. 2014 ; 6(4):e20055. doi: 10.5812/numonthly.20055.

Copyright © 2014, Nephrology and Urology Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Kim HY. Nutritional intervention for a patient with diabetic nephropathy. Clin Nutr Res. 2014; 3(1): 64-8[DOI][PubMed]
  • 2. Thompson DD. Aging and sarcopenia. J Musculoskelet Neuronal Interact. 2007; 7(4): 344-5[PubMed]
  • 3. Foley RN, Wang C, Ishani A, Collins AJ, Murray AM. Kidney function and sarcopenia in the United States general population: NHANES III. Am J Nephrol. 2007; 27(3): 279-86[DOI][PubMed]
  • 4. Domanski M, Ciechanowski K. Sarcopenia: a major challenge in elderly patients with end-stage renal disease. J Aging Res. 2012; 2012: 754739[DOI][PubMed]
  • 5. Cawthon PM, Marshall LM, Michael Y, Dam TT, Ensrud KE, Barrett-Connor E, et al. Frailty in older men: prevalence, progression, and relationship with mortality. J Am Geriatr Soc. 2007; 55(8): 1216-23[DOI][PubMed]
  • 6. Lauretani F, Russo CR, Bandinelli S, Bartali B, Cavazzini C, Di Iorio A, et al. Age-associated changes in skeletal muscles and their effect on mobility: an operational diagnosis of sarcopenia. J Appl Physiol (1985). 2003; 95(5): 1851-60[DOI][PubMed]
  • 7. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010; 39(4): 412-23[DOI][PubMed]
  • 8. Rolland Y, Lauwers-Cances V, Cournot M, Nourhashemi F, Reynish W, Riviere D, et al. Sarcopenia, calf circumference, and physical function of elderly women: a cross-sectional study. J Am Geriatr Soc. 2003; 51(8): 1120-4[PubMed]
  • 9. Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF, 3rd, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009; 150(9): 604-12[PubMed]
  • 10. Chien MY, Kuo HK, Wu YT. Sarcopenia, cardiopulmonary fitness, and physical disability in community-dwelling elderly people. Phys Ther. 2010; 90(9): 1277-87[DOI][PubMed]
  • 11. Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc. 2002; 50(5): 889-96[PubMed]
  • 12. Bijlsma AY, Meskers CG, Ling CH, Narici M, Kurrle SE, Cameron ID, et al. Defining sarcopenia: the impact of different diagnostic criteria on the prevalence of sarcopenia in a large middle aged cohort. Age (Dordr). 2013; 35(3): 871-81[DOI][PubMed]
  • 13. Morley JE. Sarcopenia: diagnosis and treatment. J Nutr Health Aging. 2008; 12(7): 452-6[PubMed]
  • 14. Jensen GL. Inflammation: roles in aging and sarcopenia. JPEN J Parenter Enteral Nutr. 2008; 32(6): 656-9[DOI][PubMed]
  • 15. Schaap LA, Pluijm SM, Deeg DJ, Visser M. Inflammatory markers and loss of muscle mass (sarcopenia) and strength. Am J Med. 2006; 119(6): 526 e9-17[DOI][PubMed]
  • 16. Manders RJ, Little JP, Forbes SC, Candow DG. Insulinotropic and muscle protein synthetic effects of branched-chain amino acids: potential therapy for type 2 diabetes and sarcopenia. Nutrients. 2012; 4(11): 1664-78[DOI][PubMed]
  • 17. Cruz-Jentoft AJ, Landi F, Topinkova E, Michel JP. Understanding sarcopenia as a geriatric syndrome. Curr Opin Clin Nutr Metab Care. 2010; 13(1): 1-7[DOI][PubMed]
  • 18. Sayer AA, Robinson SM, Patel HP, Shavlakadze T, Cooper C, Grounds MD. New horizons in the pathogenesis, diagnosis and management of sarcopenia. Age Ageing. 2013; 42(2): 145-50[DOI][PubMed]
  • 19. Di Monaco M, Vallero F, Di Monaco R, Tappero R. Prevalence of sarcopenia and its association with osteoporosis in 313 older women following a hip fracture. Arch Gerontol Geriatr. 2011; 52(1): 71-4[DOI][PubMed]
  • 20. Bucci L, Yani SL, Fabbri C, Bijlsma AY, Maier AB, Meskers CG, et al. Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects. Biogerontology. 2013; 14(3): 261-72[DOI][PubMed]
  • 21. Solerte SB, Gazzaruso C, Bonacasa R, Rondanelli M, Zamboni M, Basso C, et al. Nutritional supplements with oral amino acid mixtures increases whole-body lean mass and insulin sensitivity in elderly subjects with sarcopenia. Am J Cardiol. 2008; 101(11A): 69-77[DOI][PubMed]
  • 22. Leal VO, Stockler-Pinto MB, Farage NE, Aranha LN, Fouque D, Anjos LA, et al. Handgrip strength and its dialysis determinants in hemodialysis patients. Nutrition. 2011; 27(11-12): 1125-9[DOI][PubMed]
  • 23. Yoda M, Inaba M, Okuno S, Yoda K, Yamada S, Imanishi Y, et al. Poor muscle quality as a predictor of high mortality independent of diabetes in hemodialysis patients. Biomed Pharmacother. 2012; 66(4): 266-70[DOI][PubMed]
  • 24. Chang YT, Wu HL, Guo HR, Cheng YY, Tseng CC, Wang MC, et al. Handgrip strength is an independent predictor of renal outcomes in patients with chronic kidney diseases. Nephrol Dial Transplant. 2011; 26(11): 3588-95[DOI][PubMed]
  • 25. Leal VO, Mafra D, Fouque D, Anjos LA. Use of handgrip strength in the assessment of the muscle function of chronic kidney disease patients on dialysis: a systematic review. Nephrol Dial Transplant. 2011; 26(4): 1354-60[DOI][PubMed]
  • 26. Desmet C, Beguin C, Swine C, Jadoul M, Universite Catholique de Louvain Collaborative G. Falls in hemodialysis patients: prospective study of incidence, risk factors, and complications. Am J Kidney Dis. 2005; 45(1): 148-53[PubMed]
  • 27. Ball AM, Gillen DL, Sherrard D, Weiss NS, Emerson SS, Seliger SL, et al. Risk of hip fracture among dialysis and renal transplant recipients. JAMA. 2002; 288(23): 3014-8[PubMed]
  • 28. Bischoff Ferrari HA. Validated treatments and therapeutic perspectives regarding nutritherapy. J Nutr Health Aging. 2009; 13(8): 737-41[PubMed]
  • 29. Broe KE, Chen TC, Weinberg J, Bischoff-Ferrari HA, Holick MF, Kiel DP. A higher dose of vitamin d reduces the risk of falls in nursing home residents: a randomized, multiple-dose study. J Am Geriatr Soc. 2007; 55(2): 234-9[DOI][PubMed]
  • 30. Marantes I, Achenbach SJ, Atkinson EJ, Khosla S, Melton LJ, 3rd, Amin S. Is vitamin D a determinant of muscle mass and strength? J Bone Miner Res. 2011; 26(12): 2860-71[DOI][PubMed]
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