Nephro-Urology Monthly

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Nephrotoxic Effect of Gentamicin and Amikacin in Neonates with Infection

Saeed Alinejad 1 , Parsa Yousefichaijan 2 , Masoud Rezagholizamenjany 3 , * , Yosef Rafie 3 , Manijeh Kahbazi 4 and Ali Arjmand 1
Authors Information
1 Department of Pediatric, Assistant Professor of Pediatric, Arak University of Medical Sciences, Arak, Iran
2 Amir Kabir Hospital, Department of Pediatric Nephrology, Associate Professor of Pediatric Nephrology, Arak University of Medical Sciences, Arak, Iran
3 School of Medicine, Arak University of Medical Sciences, Arak, Iran
4 Department of Pediatric, Associate Professor of Pediatric, Arak University of Medical Sciences, Arak, Iran
Article information
  • Nephro-Urology Monthly: March 2018, 10 (2); e58580
  • Published Online: March 10, 2018
  • Article Type: Research Article
  • Received: July 23, 2017
  • Accepted: February 3, 2018
  • DOI: 10.5812/numonthly.58580

To Cite: Alinejad S, Yousefichaijan P, Rezagholizamenjany M, Rafie Y, Kahbazi M, et al. Nephrotoxic Effect of Gentamicin and Amikacin in Neonates with Infection, Nephro-Urol Mon. 2018 ;10(2):e58580. doi: 10.5812/numonthly.58580.

Abstract
Copyright: Copyright © 2018, Nephro-Urology Monthly. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Methods
3. Results
4. Discussion
Acknowledgements
Footnote
References
  • 1. Gallardo-Godoy A, Muldoon C, Becker B, Elliott AG, Lash LH, Huang JX, et al. Activity and Predicted Nephrotoxicity of Synthetic Antibiotics Based on Polymyxin B. J Med Chem. 2016;59(3):1068-77. doi: 10.1021/acs.jmedchem.5b01593. [PubMed: 26734854].
  • 2. Rezagholi-Zamnjany M, Yousefichaijan P. An overview on peritoneal dialysis. Ann Res Dial. 2016;1(1).
  • 3. Saban JA, Pizzi M, Caldwell J, Palijan A, Zappitelli M. Previous aminoglycoside use and acute kidney injury risk in non-critically ill children. Pediatr Nephrol. 2017;32(1):173-9. doi: 10.1007/s00467-016-3471-9. [PubMed: 27718084].
  • 4. Picard W, Bazin F, Clouzeau B, Bui HN, Soulat M, Guilhon E, et al. Propensity-based study of aminoglycoside nephrotoxicity in patients with severe sepsis or septic shock. Antimicrob Agents Chemother. 2014;58(12):7468-74. doi: 10.1128/AAC.03750-14. [PubMed: 25288085].
  • 5. Lau L, Al-Ismaili Z, Harel-Sterling M, Pizzi M, Caldwell JS, Piccioni M, et al. Serum cystatin C for acute kidney injury evaluation in children treated with aminoglycosides. Pediatr Nephrol. 2017;32(1):163-71. doi: 10.1007/s00467-016-3450-1. [PubMed: 27743042].
  • 6. Mingeot-Leclercq MP, Décout JL. Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside antibiotics and emergence of amphiphilic aminoglycosides. Med Chem Comm. 2016;7(4):586-611. doi: 10.1039/c5md00503e.
  • 7. Denamur S, Boland L, Beyaert M, Verstraeten SL, Fillet M, Tulkens PM, et al. Subcellular mechanisms involved in apoptosis induced by aminoglycoside antibiotics: Insights on p53, proteasome and endoplasmic reticulum. Toxicol Appl Pharmacol. 2016;309:24-36. doi: 10.1016/j.taap.2016.08.020. [PubMed: 27568863].
  • 8. Downes KJ, Patil NR, Rao MB, Koralkar R, Harris WT, Clancy JP, et al. Risk factors for acute kidney injury during aminoglycoside therapy in patients with cystic fibrosis. Pediatr Nephrol. 2015;30(10):1879-88. doi: 10.1007/s00467-015-3097-3. [PubMed: 25912993].
  • 9. Bajracharya S, Pandey K, Haque A. To evaluate the creatinine clearance and compare nephrotoxic potential of amikacin and gentamicin, in post-operative patients with normal baseline renal function. Int J Basic Clin Pharmacol. 2017;5(5):1942-8.
  • 10. Sweileh WM. A prospective comparative study of gentamicin- and amikacin-induced nephrotoxicity in patients with normal baseline renal function. Fundam Clin Pharmacol. 2009;23(4):515-20. doi: 10.1111/j.1472-8206.2009.00702.x. [PubMed: 19709328].
  • 11. Dayan N, Dabbah H, Weissman I, Aga I, Even L, Glikman D. Urinary tract infections caused by community-acquired extended-spectrum beta-lactamase-producing and nonproducing bacteria: a comparative study. J Pediatr. 2013;163(5):1417-21. doi: 10.1016/j.jpeds.2013.06.078. [PubMed: 23919903].
  • 12. Sassen MC, Kim SW, Kwon TH, Knepper MA, Miller RT, Frokiaer J, et al. Dysregulation of renal sodium transporters in gentamicin-treated rats. Kidney Int. 2006;70(6):1026-37. doi: 10.1038/sj.ki.5001654. [PubMed: 16850027].
  • 13. Takamoto K, Kawada M, Usui T, Ishizuka M, Ikeda D. Aminoglycoside antibiotics reduce glucose reabsorption in kidney through down-regulation of SGLT1. Biochem Biophys Res Commun. 2003;308(4):866-71. doi: 10.1016/S0006-291X(03)01502-X. [PubMed: 12927799].
  • 14. Akbari R, Javaniyan M, Fahimi A, Sadeghi M. Renal function in patients with diabetic foot infection; does antibiotherapy affect it?. J Renal Inj Prev. 2017;6(2):117-21. doi: 10.15171/jrip.2017.23. [PubMed: 28497087].
  • 15. Wolf G, Ritz E. Diabetic nephropathy in type 2 diabetes prevention and patient management. J Am Soc Nephrol. 2003;14(5):1396-405. doi: 10.1097/01.ASN.0000065639.19190.CF. [PubMed: 12707409].
  • 16. Pannell WC, Banks K, Hahn J, Inaba K, Marecek GS. Antibiotic related acute kidney injury in patients treated for open fractures. Injury. 2016;47(3):653-7. doi: 10.1016/j.injury.2016.01.018. [PubMed: 26854072].
  • 17. Roger C, Nucci B, Louart B, Friggeri A, Knani H, Evrard A, et al. Impact of 30 mg/kg amikacin and 8 mg/kg gentamicin on serum concentrations in critically ill patients with severe sepsis. J Antimicrob Chemother. 2016;71(1):208-12. doi: 10.1093/jac/dkv291. [PubMed: 26429564].
  • 18. Sonia SF, Hassan MS, Ara F, Hanif M. Fractional excretion of magnesium, a marker of aminoglycoside induced nephrotoxicity in neonates. Saudi J Kidney Dis Transpl. 2016;27(5):902-7. doi: 10.4103/1319-2442.190781. [PubMed: 27751996].
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