Nephro-Urology Monthly

Published by: Kowsar

Primary Renal Primitive Neuroectodermal Tumor/Ewing’s Sarcoma Imaging and Pathologic Findings of a Patient with a Nine Year, Eight Month Disease Free Period: Case Report and Review of Literature

Ivan Zokalj 1 , * , Jasminka Igrec 1 and Antonio Plesnar 2
Authors Information
1 Department of Radiology, County Hospital Cakovec, Cakovec, Croatia
2 Department of Surgery, Division of Urology, County Hospital Cakovec, Cakovec, Croatia
Article information
  • Nephro-Urology Monthly: July 2016, 8 (4); e58812
  • Published Online: July 18, 2016
  • Article Type: Case Report
  • Received: March 18, 2016
  • Accepted: April 30, 2016
  • DOI: 10.5812/numonthly.37950

To Cite: Zokalj I, Igrec J, Plesnar A. Primary Renal Primitive Neuroectodermal Tumor/Ewing’s Sarcoma Imaging and Pathologic Findings of a Patient with a Nine Year, Eight Month Disease Free Period: Case Report and Review of Literature, Nephro-Urol Mon. 2016 ; 8(4):e58812. doi: 10.5812/numonthly.37950.

Abstract
Copyright © 2016, Nephrology and Urology Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
Acknowledgements
Footnote
References
  • 1. Parham DM, Roloson GJ, Feely M, Green DM, Bridge JA, Beckwith JB. Primary malignant neuroepithelial tumors of the kidney: a clinicopathologic analysis of 146 adult and pediatric cases from the National Wilms' Tumor Study Group Pathology Center. Am J Surg Pathol. 2001; 25(2): 133-46[PubMed]
  • 2. Lin PP, Brody RI, Hamelin AC, Bradner JE, Healey JH, Ladanyi M. Differential transactivation by alternative EWS-FLI1 fusion proteins correlates with clinical heterogeneity in Ewing's sarcoma. Cancer Res. 1999; 59(7): 1428-32[PubMed]
  • 3. Jimenez RE, Folpe AL, Lapham RL, Ro JY, O'Shea PA, Weiss SW, et al. Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney: a clinicopathologic and immunohistochemical analysis of 11 cases. Am J Surg Pathol. 2002; 26(3): 320-7[PubMed]
  • 4. Gonlusen G, Ergin M, Paydas S, Bolat FA. Primitive neuroectodermal tumor of the kidney: a rare entity. Int Urol Nephrol. 2001; 33(3): 449-51[PubMed]
  • 5. Ellinger J, Bastian PJ, Hauser S, Biermann K, Muller SC. Primitive neuroectodermal tumor: rare, highly aggressive differential diagnosis in urologic malignancies. Urology. 2006; 68(2): 257-62[DOI][PubMed]
  • 6. Hakky TS, Gonzalvo AA, Lockhart JL, Rodriguez AR. Primary Ewing sarcoma of the kidney: a symptomatic presentation and review of the literature. Ther Adv Urol. 2013; 5(3): 153-9[DOI][PubMed]
  • 7. Seemayer TA, Thelmo WL, Bolande RP, Wiglesworth FW. Peripheral neuroectodermal tumors. Perspect Pediatr Pathol. 1975; 2: 151-72[PubMed]
  • 8. Ohgaki K, Horiuchi K, Mizutani S, Sato M, Kondo Y. Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney that responded to low-dose chemotherapy with ifosfamide, etoposide, and doxorubicin. Int J Clin Oncol. 2010; 15(2): 210-4[DOI][PubMed]
  • 9. Kuczynski AP, Gugelmin ES, Netto RA. [Primitive neuroectodermal tumor of the kidney in children]. J Pediatr (Rio J). 2001; 77(1): 49-51[PubMed]
  • 10. Maccioni F, Della Rocca C, Salvi PF, Manicone AM, Ascarelli A, Longo F, et al. Malignant peripheral neuroectodermal tumor (MPNET) of the kidney. Abdom Imaging. 2000; 25(1): 103-6[PubMed]
  • 11. Ba L, Tan H, Xiao H, Guan Y, Gao J, Gao X. Radiologic and clinicopathologic findings of peripheral primitive neuroectodermal tumors. Acta Radiol. 2015; 56(7): 820-8[DOI][PubMed]
  • 12. Bing Z, Zhang P, Tomaszewski JE, Maclennan GT. Primary Ewing sarcoma/primitive neuroectodermal tumor of the kidney. J Urol. 2009; 181(3): 1341-2[DOI][PubMed]
  • 13. Weidner N, Tjoe J. Immunohistochemical profile of monoclonal antibody O13: antibody that recognizes glycoprotein p30/32MIC2 and is useful in diagnosing Ewing's sarcoma and peripheral neuroepithelioma. Am J Surg Pathol. 1994; 18(5): 486-94[PubMed]
  • 14. Folpe AL, Hill CE, Parham DM, O'Shea PA, Weiss SW. Immunohistochemical detection of FLI-1 protein expression: a study of 132 round cell tumors with emphasis on CD99-positive mimics of Ewing's sarcoma/primitive neuroectodermal tumor. Am J Surg Pathol. 2000; 24(12): 1657-62[PubMed]
  • 15. Le Deley MC, Delattre O, Schaefer KL, Burchill SA, Koehler G, Hogendoorn PC, et al. Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial. J Clin Oncol. 2010; 28(12): 1982-8[DOI][PubMed]
  • 16. Miser JS, Kinsella TJ, Triche TJ, Steis R, Tsokos M, Wesley R, et al. Treatment of peripheral neuroepithelioma in children and young adults. J Clin Oncol. 1987; 5(11): 1752-8[PubMed]
  • 17. Grier HE, Krailo MD, Tarbell NJ, Link MP, Fryer CJ, Pritchard DJ, et al. Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone. N Engl J Med. 2003; 348(8): 694-701[DOI][PubMed]
  • 18. Ladenstein R, Potschger U, Le Deley MC, Whelan J, Paulussen M, Oberlin O, et al. Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial. J Clin Oncol. 2010; 28(20): 3284-91[DOI][PubMed]
  • 19. Risi E, Iacovelli R, Altavilla A, Alesini D, Palazzo A, Mosillo C, et al. Clinical and pathological features of primary neuroectodermal tumor/Ewing sarcoma of the kidney. Urology. 2013; 82(2): 382-6[DOI][PubMed]
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