Nephro-Urology Monthly

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Pregnancy and Renal Transplantation

Sepideh Khodaverdi 1 , * , Robabeh Mohammadbeigi 1 , Mansoureh Vahdat 1 , Shahla Mirgalooy Bayat 1 and Maryam Khodaverdi 2
Authors Information
1 Endometriosis Research Center, Rasool-e-Akram Complex Hospital, Iran University of Medical Sciences, Tehran, Iran.
2 Department of Anesthesiology, Iran University of Medical Sciences, Tehran, Iran.
Article information
  • Nephro-Urology Monthly: May 2018, 10 (3); e63052
  • Published Online: April 7, 2018
  • Article Type: Review Article
  • Received: November 15, 2017
  • Revised: January 27, 2018
  • Accepted: March 7, 2018
  • DOI: 10.5812/numonthly.63052

To Cite: Khodaverdi S, Mohammadbeigi R, Vahdat M, Mirgalooy Bayat S, Khodaverdi M. Pregnancy and Renal Transplantation, Nephro-Urol Mon. 2018 ; 10(3):e63052. doi: 10.5812/numonthly.63052.

Copyright © 2018, Nephro-Urology Monthly. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Introduction
2. Methods
3. Results
4. Discussion
5. Conclusions
  • 1. Nevis IF, Reitsma A, Dominic A, McDonald S, Thabane L, Akl EA, et al. Pregnancy outcomes in women with chronic kidney disease: a systematic review. Clin J Am Soc Nephrol. 2011;6(11):2587-98. doi: 10.2215/CJN.10841210. [PubMed: 21940842].
  • 2. Hebral AL, Cointault O, Connan L, Congy-Jolivet N, Esposito L, Cardeau-Desangles I, et al. Pregnancy after kidney transplantation: outcome and anti-human leucocyte antigen alloimmunization risk. Nephrol Dial Transplant. 2014;29(9):1786-93. doi: 10.1093/ndt/gfu208. [PubMed: 24914091].
  • 3. Yilmaz N, Yilmaz UE, Unal A, Unal E, Titiz I. Delivery in female kidney transplant recipients with hepatitis C virus infection: is it safe for mother and newborn? Prog Transplant. 2012;22(2):141-4. 154. doi: 10.7182/pit2012667. [PubMed: 22878070].
  • 4. Deshpande NA, James NT, Kucirka LM, Boyarsky BJ, Garonzik-Wang JM, Montgomery RA, et al. Pregnancy outcomes in kidney transplant recipients: a systematic review and meta-analysis. Am J Transplant. 2011;11(11):2388-404. doi: 10.1111/j.1600-6143.2011.03656.x. [PubMed: 21794084].
  • 5. Watnick S. Pregnancy and contraceptive counseling of women with chronic kidney disease and kidney transplants. Adv Chronic Kidney Dis. 2007;14(2):126-31. doi: 10.1053/j.ackd.2007.01.003. [PubMed: 17395115].
  • 6. Davison JM, Bailey DJ. Pregnancy following renal transplantation. J Obstet Gynaecol Res. 2003;29(4):227-33. doi: 10.1046/j.1341-8076.2003.00106.x.
  • 7. Murray JE, Reid DE, Harrison JH, Merrill JP. Successful pregnancies after human renal transplantation. N Engl J Med. 1963;269:341-3. doi: 10.1056/NEJM196308152690704. [PubMed: 13936776].
  • 8. Jungers P, Chauveau D. Pregnancy in renal disease. Kidney Int. 1997;52(4):871-85. [PubMed: 9328925].
  • 9. Ghanem ME, El-Baghdadi LA, Badawy AM, Bakr MA, Sobhe MA, Ghoneim MA. Pregnancy outcome after renal allograft transplantation: 15 years experience. Eur J Obstet Gynecol Reprod Biol. 2005;121(2):178-81. doi: 10.1016/j.ejogrb.2004.11.035. [PubMed: 16009483].
  • 10. Rahamimov R, Ben-Haroush A, Wittenberg C, Mor E, Lustig S, Gafter U, et al. Pregnancy in renal transplant recipients: long-term effect on patient and graft survival. A single-center experience. Transplantation. 2006;81(5):660-4. doi: 10.1097/ [PubMed: 16534465].
  • 11. Kashanizadeh N, Nemati E, Sharifi-Bonab M, Moghani-Lankarani M, Ghazizadeh S, Einollahi B, et al. Impact of pregnancy on the outcome of kidney transplantation. Transplant Proc. 2007;39(4):1136-8. doi: 10.1016/j.transproceed.2007.03.010. [PubMed: 17524914].
  • 12. Gorgulu N, Yelken B, Caliskan Y, Turkmen A, Sever MS. Does pregnancy increase graft loss in female renal allograft recipients? Clin Exp Nephrol. 2010;14(3):244-7. doi: 10.1007/s10157-009-0263-6. [PubMed: 20091332].
  • 13. Gutierrez MJ, Gonzalez P, Delgado I, Gutierrez E, Gonzalez E, Siqueira RC, et al. Renal allograft function and cardiovascular risk in recipients of kidney transplantation after successful pregnancy. Transplant Proc. 2009;41(6):2399-402. doi: 10.1016/j.transproceed.2009.06.042. [PubMed: 19715932].
  • 14. Kim HW, Seok HJ, Kim TH, Han DJ, Yang WS, Park SK. The experience of pregnancy after renal transplantation: pregnancies even within postoperative 1 year may be tolerable. Transplantation. 2008;85(10):1412-9. doi: 10.1097/TP.0b013e318170f8ed. [PubMed: 18497680].
  • 15. Pour-Reza-Gholi F, Nafar M, Farrokhi F, Entezari A, Taha N, Firouzan A, et al. Pregnancy in kidney transplant recipients. Transplantation proceedings. 2005;37(7):3090-2. doi: 10.1016/j.transproceed.2005.08.033.
  • 16. Kwek JL, Tey V, Yang L, Kanagalingam D, Kee T. Renal and obstetric outcomes in pregnancy after kidney transplantation: Twelve-year experience in a Singapore transplant center. J Obstet Gynaecol Res. 2015;41(9):1337-44. doi: 10.1111/jog.12736. [PubMed: 26017543].
  • 17. Rocha A, Cardoso A, Malheiro J, Martins LS, Fonseca I, Braga J, et al. Pregnancy after kidney transplantation: graft, mother, and newborn complications. Transplant Proc. 2013;45(3):1088-91. doi: 10.1016/j.transproceed.2013.02.006. [PubMed: 23622633].
  • 18. Bouattar T, Hakim H, Rhou H, Benamar L, Bayahia R, Ouzeddoun N. Pregnancy in renal transplant recipients. Transplantation proceedings. 2009;41(5):1586-8. doi: 10.1016/j.transproceed.2009.02.105.
  • 19. Al Duraihimh H, Ghamdi G, Moussa D, Shaheen F, Mohsen N, Sharma U, et al. Outcome of 234 pregnancies in 140 renal transplant recipients from five middle eastern countries. Transplantation. 2008;85(6):840-3. doi: 10.1097/TP.0b013e318166ac45. [PubMed: 18360265].
  • 20. Han D, Lee R, Kim T, Kim S, Kim S. Pregnancy after renal transplantation. Transplantation proceedings. 2000;32(7):1871–2. doi: 10.1016/S0041-1345(00)01470-6.
  • 21. Ebpg Expert Group on Renal Transplantation . European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.10. Pregnancy in renal transplant recipients. Nephrol Dial Transplant. 2002;17 Suppl 4:50-5. [PubMed: 12091650].
  • 22. Yassaee F. O1026 Pregnancy outcome in kidney transplant patient. Int J Gynecol Obstet. 2009;107:S385. doi: 10.1016/s0020-7292(09)61399-0.
  • 23. Framarino Dei Malatesta M, Rossi M, Rocca B, Iappelli M, Poli L, Piccioni MG, et al. Fertility following solid organ transplantation. Transplant Proc. 2007;39(6):2001-4. doi: 10.1016/j.transproceed.2007.05.014. [PubMed: 17692676].
  • 24. Pezeshki M, Taherian AA, Gharavy M, Ledger WL. Menstrual characteristics and pregnancy in women after renal transplantation. Int J Gynaecol Obstet. 2004;85(2):119-25. doi: 10.1016/j.ijgo.2003.09.013. [PubMed: 15099772].
  • 25. Coscia LA, Constantinescu S, Moritz MJ, Frank AM, Ramirez CB, Doria C, et al. Report from the National Transplantation Pregnancy Registry (NTPR): outcomes of pregnancy after transplantation. Clin Transpl. 2008:89-105. [PubMed: 19708448].
  • 26. Sibanda N, Briggs JD, Davison JM, Johnson RJ, Rudge CJ. Pregnancy after organ transplantation: a report from the UK Transplant pregnancy registry. Transplantation. 2007;83(10):1301-7. doi: 10.1097/ [PubMed: 17519778].
  • 27. Di Loreto P, Martino F, Chiaramonte S, Dissegna D, Ronco C, Marchesoni D, et al. Pregnancy after kidney transplantation: two transplantation centers--Vicenza-Udine experience. Transplant Proc. 2010;42(4):1158-61. doi: 10.1016/j.transproceed.2010.03.082. [PubMed: 20534249].
  • 28. Bramham K, Nelson-Piercy C, Gao H, Pierce M, Bush N, Spark P, et al. Pregnancy in renal transplant recipients: a UK national cohort study. Clin J Am Soc Nephrol. 2013;8(2):290-8. doi: 10.2215/CJN.06170612. [PubMed: 23085724].
  • 29. Yildirim Y, Uslu A. Pregnancy in patients with previous successful renal transplantation. Int J Gynaecol Obstet. 2005;90(3):198-202. doi: 10.1016/j.ijgo.2005.05.009. [PubMed: 16043182].
  • 30. Levidiotis V, Chang S, McDonald S. Pregnancy and maternal outcomes among kidney transplant recipients. J Am Soc Nephrol. 2009;20(11):2433-40. doi: 10.1681/ASN.2008121241. [PubMed: 19797167].
  • 31. Watnick S, Rueda J. Reproduction and contraception after kidney transplantation. Curr Opin Obstet Gynecol. 2008;20(3):308-12. doi: 10.1097/GCO.0b013e3282f8b009. [PubMed: 18460947].
  • 32. Mastrobattista JM, Katz AR. Pregnancy after organ transplant. Obstet Gynecol Clin North Am. 2004;31(2):415-28. vii. doi: 10.1016/j.ogc.2004.03.005. [PubMed: 15200970].
  • 33. Duley L, Henderson-Smart DJ, Knight M, King JF. Antiplatelet agents for preventing pre-eclampsia and its complications. Cochrane Database Syst Rev. 2004;(1). CD004659. doi: 10.1002/14651858.CD004659. [PubMed: 14974075].
  • 34. National Institute for Health and Clinical Excellence . Hypertension in Pregnancy. The Management of Hypertensive Disorders During Pregnancy. London; 2010.
  • 35. Sgro MD, Barozzino T, Mirghani HM, Sermer M, Moscato L, Akoury H, et al. Pregnancy outcome post renal transplantation. Teratology. 2002;65(1):5-9. doi: 10.1002/tera.1092. [PubMed: 11835226].
  • 36. Areia A, Galvao A, Pais MS, Freitas L, Moura P. Outcome of pregnancy in renal allograft recipients. Arch Gynecol Obstet. 2009;279(3):273-7. doi: 10.1007/s00404-008-0711-7. [PubMed: 18568355].
  • 37. Richman K, Gohh R. Pregnancy after renal transplantation: a review of registry and single-center practices and outcomes. Nephrol Dial Transplant. 2012;27(9):3428-34. doi: 10.1093/ndt/gfs276. [PubMed: 22815546].

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